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MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer

✍ Scribed by Reeves, Stuart G; Meldrum, Cliff; Groombridge, Claire; Spigelman, Allan D; Suchy, Janina; Kurzawski, Grzegorz; Lubinski, Jan; McElduff, Patrick; Scott, Rodney J


Book ID
109848839
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
173 KB
Volume
17
Category
Article
ISSN
1018-4813

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## Abstract Polymorphisms in the 2 cell‐cycle control genes __Aurora A__ and __Cyclin D1__ have previously been associated with changes in the age of onset of colorectal cancer in persons harboring germline mutations in DNA mismatch repair genes associated with hereditary nonpolyposis colorectal ca