Spectrophotometric Determination of Procaine in Procaine Penicillin G
โ Scribed by St. John, C.V.
- Publisher
- Elsevier
- Year
- 1948
- Weight
- 182 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0095-9553
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๐ SIMILAR VOLUMES
Chromatographic systems are described which are suitable for the examination of procaine penicillin G preparations which may contain, in addition to procaine and penicillin G, the degradation products paminobenzoic acid, ethyl p-aminobenzoate, benzylpenicilloic acid, and benzylpenillic acid. Further
Quantitative studies were made o n the effects of various additives such as procaine hydrochloride, dextrose, and citrate in reducing penicillin G procaine solubility in water. Aqueous vehicles were prepared i n which the solubility was lowered to a minimum of 0.036 mg./cc. at room temperature. ONG