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Spectrophotometric determination of cystine by formation of an o-phthalaldehyde/N-acetyl-l-cysteine derivative

✍ Scribed by M.J.Medina Hernández; R.M.Villanueva Camañas; M.C.Garcia Alvarez-Coque

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
285 KB
Volume
40
Category
Article
ISSN
0026-265X

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Determination of eflornithine enantiomer
Determination of eflornithine enantiomers in plasma by precolumn derivatization with o-phthalaldehyde-N-acetyl-l-cysteine and liquid chromatography with UV detection
✍ R. Jansson-Löfmark; S. Römsing; E. Albers; M. Ashton 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB 👁 1 views

## Abstract A bioanalytical method for indirect determination of eflornithine enantiomers in 75 μL human plasma has been developed and validated. l‐ and d‐eflornithine were derivatized with __o__‐phthalaldehyde and __N__‐acetyl‐L‐cysteine to generate diastereomers which were separated on two serial