๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Specific labelling of nucleosides and nucleotides with 13C and 15N

โœ Scribed by Jan Milecki

Publisher
John Wiley and Sons
Year
2002
Tongue
French
Weight
308 KB
Volume
45
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

Synthetic methods leading to nucleosides and deoxynucleosides specifically labelled with ^13^C and ^15^N are reviewed. The paper covers labelling the sugar part of the molecule (with ^13^C) and the aglycone part (both with ^13^C and ^15^N). Synthetic methods for labelling at every relevant site of the nucleoside molecule are discussed. The paper also presents the strategies for the synthesis of multilabelled nucleosides. Copyright ยฉ 2002 John Wiley & Sons, Ltd.

๐Ÿ“œ SIMILAR VOLUMES

Chemienzymatic Synthesis of Uridine Nucl
Chemienzymatic Synthesis of Uridine Nucleotides Labeled with [15N] and [13C]
โœ Anne-Marie Gilles; Ioan Cristea; Nicolae Palibroda; Ida Hilden; Kaj Frank Jensen ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 126 KB

tedious task. It requires isotopically labeled nucleo-UTP, labeled with 15 N and 13 C (at all carbon atoms of sides for solid-phase synthesis or the corresponding the ribose moiety), was obtained enzymatically from NTPs for in vitro transcription methods. A variety of [ 15 N]uracil and [ 13 C 6 ]glu

Use of 13C tags with specifically 15N-la
Use of 13C tags with specifically 15N-labeled DNA and RNA
โœ Josรฉ-Luis Abad; Anthony J. Shallop; Barbara L. Gaffney; Roger A. Jones ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 196 KB ๐Ÿ‘ 1 views

We describe methods to introduce 13 C specifically to the C2 or C8 positions of 15 N-multilabeled purines, thereby permitting " 13 C tagging" of all base nitrogens except the amino group of adenosine. These procedures permit the incorporation of two or more 15 N-multilabeled monomers into a given DN