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Synthesis of Stable-Isotope (13C and 15N) Labeled Nucleosides and Their Applications

โœ Scribed by Etsuko Kawashima; Kazuo Kamaike

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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We describe methods to introduce 13 C specifically to the C2 or C8 positions of 15 N-multilabeled purines, thereby permitting " 13 C tagging" of all base nitrogens except the amino group of adenosine. These procedures permit the incorporation of two or more 15 N-multilabeled monomers into a given DN