The ball-milling technique was used under solvent-free conditions to perform a Horner-Wadsworth-Emmons reaction in the presence of a mild carbonate base. Starting from a phosphonate-substituted glycine, this method gave access to Boc-protected unsaturated amino esters in excellent yield and selectiv
✦ LIBER ✦
Solventless Synthesis of N -Protected Amino Acids in a Ball Mill
✍ Scribed by Konnert, Laure; Gauliard, Anne; Lamaty, Frédéric; Martinez, Jean; Colacino, Evelina
- Book ID
- 125975780
- Publisher
- American Chemical Society
- Year
- 2013
- Tongue
- English
- Weight
- 377 KB
- Volume
- 1
- Category
- Article
- ISSN
- 2168-0485
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Solvent-free synthesis of unsaturated am
✍
Alice Baron; Jean Martinez; Frédéric Lamaty
📂
Article
📅
2010
🏛
Elsevier Science
🌐
French
⚖ 446 KB
Use of ethoxyacetylene for the synthesis
✍
Banks, G. R.; Cohen, D.; Pattenden, G. E.; Thomas, J. A. G.
📂
Article
📅
1967
🏛
The Royal Society of Chemistry
🌐
English
⚖ 300 KB
Synthesis and reactions of esters of N-h
✍
G. H. L. Nefkens; G. I. Tesser; R. J. F. Nivard
📂
Article
📅
2010
🏛
Elsevier Science
🌐
English
⚖ 313 KB
## Abstract Esters can be prepared from __N__‐hydroxyphthalimide and __N__‐carbobenzoxy‐ or __N__‐phthaloyl‐amino acids using dicyclohexylcarbodi‐imide as condensing agent. The compounds are suitable for the stepwise synthesis of peptides without racemization. With methanol the __N__‐hydroxyphthali
Synthesis of C -Propargylic Esters of N-
✍
Bew, Sean P.; Hiatt-Gipson, Glyn D.
📂
Article
📅
2010
🏛
American Chemical Society
🌐
English
⚖ 740 KB
ChemInform Abstract: Solvent-Free Synthe
✍
Alice Baron; Jean Martinez; Frederic Lamaty
📂
Article
📅
2011
🏛
John Wiley and Sons
⚖ 30 KB
👁 1 views
Highly Practical Methodology for the Syn
✍
Myers, Andrew G.; Gleason, James L.; Yoon, Taeyoung; Kung, Daniel W.
📂
Article
📅
1997
🏛
American Chemical Society
🌐
English
⚖ 602 KB