✦ LIBER ✦

Synthesis and reactions of esters of N-hydroxyphthalimide and N-protected amino acids

✍ Scribed by G. H. L. Nefkens; G. I. Tesser; R. J. F. Nivard

Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 313 KB
Volume: 81
Category: Article
ISSN: 0165-0513
DOI: 10.1002/recl.19620810807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Esters can be prepared from N‐hydroxyphthalimide and N‐carbobenzoxy‐ or N‐phthaloyl‐amino acids using dicyclohexylcarbodi‐imide as condensing agent. The compounds are suitable for the stepwise synthesis of peptides without racemization. With methanol the N‐hydroxyphthalimide ester of N‐phthaloylglycine can be converted into the methyl ester of N‐phthaloylglycine.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of C-Prop

ChemInform Abstract: Synthesis of C-Propargylic Esters of N-Protected Amino Acids and Peptides.

✍ Sean P. Bew; Glyn D. Hiatt-Gipson 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

## Abstract The method works well for Boc‐ and Cbz‐protected substrates.

Catalyst and solvent-free amidation of i

Catalyst and solvent-free amidation of inactive esters of N-protected amino acids

✍ Krishna Chaitanya Nadimpally; Kishore Thalluri; Nani Babu Palakurthy; Abhijit Sa 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 290 KB

ChemInform Abstract: Biocatalytic Produc

ChemInform Abstract: Biocatalytic Production of Unnatural Amino Acids, Mono Esters, and N-Protected Derivatives

✍ I. G. FOTHERINGHAM; D. P. PANTALEONE; P. P. TAYLOR 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

Gamma irradiation of solid-state N and C

Gamma irradiation of solid-state N and C terminally protected oligopeptides and amino acids: Carbobenzoxy derivatives and esters of amino acids

✍ R. Badiello; A. Breccia; R. Budini 📂 Article 📅 1966 🏛 Elsevier Science ⚖ 438 KB

Synthesis of Amino Acids from N,N-Bis(tr

Synthesis of Amino Acids from N,N-Bis(trimethylsilyl)glycine Esters

✍ Prof. Dr. K. Rühlmann; Dipl.-Chem. G. Kuhrt 📂 Article 📅 1968 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 3 views

Pmc-protected amino acid esters as subst

Pmc-protected amino acid esters as substrates in N-alkylamino acid synthesis

✍ Kazimierz Wiśniewski; Aleksandra S. Kołodziejczyk 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 186 KB

N-alkylamino acids may be synthesised via Mitsunobu reaction of N-(2,2,5,7,8pentamethylchroman-6-sulphonyl-)-amino acid esters with various alcohols and subsequent deprotection.