𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

✍ Scribed by Cherepanov, Peter; Sun, Zhen-Yu J; Rahman, Shaila; Maertens, Goedele; Wagner, Gerhard; Engelman, Alan

Book ID
109966976
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
759 KB
Volume
12
Category
Article
ISSN
1545-9993

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Crystal Structures of Novel Allosteric P
Crystal Structures of Novel Allosteric Peptide Inhibitors of HIV Integrase Identify New Interactions at the LEDGF Binding Site
✍ Dr. David I. Rhodes; Dr. Thomas S. Peat; Dr. Nick Vandegraaff; Dharshini Jeevara πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 959 KB

## Abstract An optimised method of solution cyclisation gave us access to a series of peptides including SLKIDNLD (**2**). We investigated the crystallographic complexes of the HIV integrase (HIV‐IN) catalytic core domain with 13 of the peptides and identified multiple interactions at the binding s

Refined solution structure of the c-term
Refined solution structure of the c-terminal DNA-binding domain of human immunovirus-1 integrase
✍ Astrid P.A.M. Eijkelenboom; Remco Sprangers; Karl HΓ₯rd; Ramon A. Puras Lutzke; R πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 352 KB πŸ‘ 2 views

The structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase has been refined using nuclear magnetic resonance spectroscopy. The protein is a dimer in solution and shows a well-defined dimer interface. The folding topology of the monomer consists of a fivestranded ␀-barrel tha