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Erratum: Solution structure of the N-terminal zinc binding domain of HIV-1 integrase


Book ID
109965224
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
346 KB
Volume
4
Category
Article
ISSN
1072-8368

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The structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase has been refined using nuclear magnetic resonance spectroscopy. The protein is a dimer in solution and shows a well-defined dimer interface. The folding topology of the monomer consists of a fivestranded ␀-barrel tha

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## Abstract The HTLV‐I integrase __N__‐terminal domain [50‐residue peptide (IN50)], and a 35‐residue truncated peptide formed by residues 9–43 (IN35) have been synthesized by solid‐phase peptide synthesis. Formation of the 50‐residue zinc finger type structure through a HHCC motif has been proved b