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Refined solution structure of the dimeric N-terminal HHCC domain of HIV-2 integrase

โœ Scribed by Astrid P.A.M. Eijkelenboom; Fusinita M.I. van den Ent; Rainer Wechselberger; Ronald H.A. Plasterk; Robert Kaptein; Rolf Boelens


Book ID
110262471
Publisher
Springer Netherlands
Year
2000
Tongue
English
Weight
174 KB
Volume
18
Category
Article
ISSN
0925-2738

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Refined solution structure of the c-term
โœ Astrid P.A.M. Eijkelenboom; Remco Sprangers; Karl Hรฅrd; Ramon A. Puras Lutzke; R ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 352 KB ๐Ÿ‘ 2 views

The structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase has been refined using nuclear magnetic resonance spectroscopy. The protein is a dimer in solution and shows a well-defined dimer interface. The folding topology of the monomer consists of a fivestranded โค-barrel tha