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Solid support synthesis of highly functionalized pyrazoles and isoxazoles; Scaffolds for molecular diversity

โœ Scribed by Andreas L. Marinnzik; Eduard R. Felder


Book ID
103405504
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
225 KB
Volume
37
Category
Article
ISSN
0040-4039

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Solid phase synthesis of a molecular lib
โœ Giovanni Pellegrino; Francesco Leonetti; Angelo Carotti; Orazio Nicolotti; Leona ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 270 KB

A small molecular library of 40 pyrimidine, pyrazole, and isoxazole derivatives, bearing structural features for a promising binding of therapeutically interesting enzymes, was designed and prepared. An efficient and straightforward solid phase synthesis was envisaged and carried out on a Rink amide