The solid phase synthesis of cyclic ureas and thioureas is described. The reduction of acylated dipeptides followed by treatment with carbonyldiimidazole or thiocarbonyldiimidazole affords the corresponding cyclic urea or thiourea in good yield and high purity. This is an example of a broader approa
β¦ LIBER β¦
Solid-Phase Synthesis of Substituted Imidazoline-Tethered 2,3-Diketopiperazines, Cyclic Ureas, and Cyclic Thioureas
β Scribed by Acharya, Achyuta N.; Ostresh, John M.; Houghten, Richard A.
- Book ID
- 126201329
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 105 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1520-4766
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