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Backbone Amide Linker (BAL) Strategy for Solid-Phase Synthesis of C-Terminal-Modified and Cyclic Peptides 1,2,3

✍ Scribed by Jensen, Knud J.; Alsina, Jordi; Songster, Michael F.; Vágner, Josef; Albericio, Fernando; Barany, George

Book ID
120043471
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
289 KB
Volume
120
Category
Article
ISSN
0002-7863

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

A modified backbone amide linker (BAL) s
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A new variation of the Backbone Amide Linker (BAL) approach has been developed for N a -Fmoc solidphase synthesis (SPS) of C-terminal modi®ed peptides; this provides a convenient route to peptides containing prolyl, N-alkylamino acyl, or histidyl derivatives at the C-terminus. To illustrate the prin