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Backbone amide linker (BAL) strategy for Nα-9-fluorenylmethoxycarbonyl (Fmoc) solid-phase synthesis of peptide aldehydes

✍ Scribed by Joseph C. Kappel; George Barany


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
183 KB
Volume
11
Category
Article
ISSN
1075-2617

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

A modified backbone amide linker (BAL) s
✍ Jordi Alsina; T.Scott Yokum; Fernando Albericio; George Barany * 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 116 KB

A new variation of the Backbone Amide Linker (BAL) approach has been developed for N a -Fmoc solidphase synthesis (SPS) of C-terminal modi®ed peptides; this provides a convenient route to peptides containing prolyl, N-alkylamino acyl, or histidyl derivatives at the C-terminus. To illustrate the prin