The solid-phase synthesis of a novel class of retro and retro-inverso peptides featuring a 2[NHCH(CF 3 )] surrogate of the classical (NHÀCO) retro-peptide bond has been accomplished. Wang resin bound a-amino esters 2 were engaged in Michael-type N-additions with 3-(E-enoyl)-1,3-oxazolidin-2one 3, wh
✦ LIBER ✦
Solid phase synthesis of retro-inverso peptide analogues
✍ Scribed by BONELLI, FABIO ;PESSI, ANTONELLO ;VERDINI, ANTONIO S.
- Book ID
- 115098235
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 235 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0367-8377
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