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Solid phase synthesis of peptide C-terminal semicarbazones and aldehydes

✍ Scribed by Jennifer A. Patterson; Robert Ramage

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 179 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)01219-8

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✦ Synopsis

A new linker based on the dibenzosuberyl system was developed in order to synthesis¢ peptide Cterminal semicarbazones which can b¢ readily converted into peptide (7-terminal aldehydes. The method uses Fmoc-methodoiogy and proceeds with no loss of stereochemical integrity.

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