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Solid phase synthesis of aspartyl peptide aldehydes

✍ Scribed by Xiao-He Tong; Anita Hong

Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 68 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)01615-4

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✦ Synopsis

An efficient method for the solid phase synthesis of aspartyl aldehyde peptides has been developed. It uses a low cost synthetic process for the preparation of Fmoc-protected Weinreb amide linker. This procedure covers several tetrapeptide aspartyl aldehydes as well as biotinylated tetrapeptide aspartyl aldehydes.

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