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Synthesis of peptide aldehydes on solid support

✍ Scribed by Marielle Paris; Catherine Pothion; Laurent Goulleux; Annie Heitz; Jean Martinez; Jean-Alain Fehrentz

Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
162 KB
Volume
41
Category
Article
ISSN
1381-5148

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πŸ“œ SIMILAR VOLUMES

Synthesis of peptide aldehydes on solid
Synthesis of peptide aldehydes on solid support using ozonolysis
✍ Marielle Paris; annie Heitz; Vincent Guerlavais; MichΓ¨le Cristau; Jean-Alain Feh πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 204 KB

A new strategy for the synthesis of peptide aldehydes on solid support is presented. Reaction of a N-protected or-amino aldehyde with MBHA-supported Wittig ou Winig-Horner reagent yielded resin-linked ~-~-unsaturated 8-amino derivative. After elongation of the peptide chain, ozonolysis produced fair