Solid-Phase Synthesis of Multiantennary Oligonucleotide Glycoconjugates Utilizing On-Support Oximation
✍ Scribed by Katajisto, Johanna; Virta, Pasi; Lönnberg, Harri
- Book ID
- 127060578
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 125 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1043-1802
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📜 SIMILAR VOLUMES
## Abstract Oligonucleotides containing terminal phosphate groups serve as useful intermediates for different applications in molecular and cell biology, as well as for diagnostic purposes. The chemical synthesis of these derivatives has been an important topic of oligonucleotide research. We repor
Linker phosphoramidite reagents containing a protected nucleoside with a cleavable 3%-ester linkage to either succinic acid, diglycolic acid, or hydroquinone-O,O%-diacetic acid (Q-Linker) allow the 3%-terminal nucleoside of an oligonucleotide sequence to be attached to underivatized 'Universal' amin