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Solid Phase Synthesis of C-Terminal Peptide Aldehydes

✍ Scribed by Fehrentz, J. A.; Paris, M.; Heitz, A.; Velek, J.; Winternitz, F.; Martinez, J.


Book ID
121882324
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
275 KB
Volume
62
Category
Article
ISSN
0022-3263

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Solid phase synthesis of peptide C-termi
✍ Jennifer A. Patterson; Robert Ramage πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 179 KB

A new linker based on the dibenzosuberyl system was developed in order to synthesisΒ’ peptide Cterminal semicarbazones which can bΒ’ readily converted into peptide (7-terminal aldehydes. The method uses Fmoc-methodoiogy and proceeds with no loss of stereochemical integrity.