Solid-phase synthesis of a folate conjugate of a DNA binding polyamide

✍ Scribed by Sanjay K. Sharma; J.William Lown

• Book ID: 104251782
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 68 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01448-x

✦ Synopsis

Solid-phase synthesis of a folate tripyrrolocarboxamide conjugate 8 of a DNA binding polyamide is described. The synthesis of a new building block monomer Boc-Py-[(CH 2 ) 3 -NHFmoc] acid 3 is also reported.