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Singlet oxygen oxidation of phosphites to phosphates

✍ Scribed by Bolduc, Paul R.; Goe, Gerald L.


Book ID
111871237
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
272 KB
Volume
39
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES


Nonaqueous oxidation of nucleoside phosp
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Summay : Bis (trimethylsilyl) peroxide, t-butyl hydroperoxide, cumene hydroperoxide, and N-methylmorpholine N-oxide serve as excellent agents for anhydrous oxidation of nucleoside phosphites to the phosphates. The reaction using bis (trimethylsilyl) peroxide is conspicuously accelerated by added tr

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m-Chloroperbenzoic acid in methylene chloride represents a rapid non-aqueous method for the conversion of phosphites to phosphates during oligonucleotide synthesis both in solution and on a solid support.

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