Summay : Bis (trimethylsilyl) peroxide, t-butyl hydroperoxide, cumene hydroperoxide, and N-methylmorpholine N-oxide serve as excellent agents for anhydrous oxidation of nucleoside phosphites to the phosphates. The reaction using bis (trimethylsilyl) peroxide is conspicuously accelerated by added tr
โฆ LIBER โฆ
Nonaqueous oxidation of phosphites to phosphates in nucleotide synthesis
โ Scribed by Kelvin K. Ogilvie; Mona J. Nemer
- Book ID
- 104241706
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 263 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
m-Chloroperbenzoic acid in methylene chloride represents a rapid non-aqueous method for the conversion of phosphites to phosphates during oligonucleotide synthesis both in solution and on a solid support.
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