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Simvastatin plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) as first-line chemotherapy in metastatic colorectal patients: a multicenter phase II study

✍ Scribed by Jeeyun Lee; Kyung Hae Jung; Young Suk Park; Joong Bae Ahn; Sang Jun Shin; Seock-Ah Im; Do Youn Oh; Dong Bok Shin; Tae Won Kim; Namsu Lee; Jae Ho Byun; Yong Sang Hong; Joon Oh Park; Se Hoon Park; Ho Yeong Lim; Won Ki Kang

Publisher
Springer
Year
2009
Tongue
English
Weight
284 KB
Volume
64
Category
Article
ISSN
0344-5704

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✍ Aziz Zaanan; Mélanie Gauthier; David Malka; Christophe Locher; Jean-Marc Gornet; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract ## BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare tumor with poor prognosis. First‐line platinum‐based chemotherapy is active in patients with advanced SBA, but data regarding second‐line chemotherapy are lacking. The aim of this study was to evaluate the efficacy and tolerabil