A phase II and pharmacokinetic study of 6S-leucovorin plus 5-fluorouracil in patients with colorectal carcinoma
β Scribed by Neal J. Meropol; Nicholas J. Petrelli; Youcef M. Rustum; Miguel Rodriguez-Bigas; Leslie E. Blumenson; Cheryl Frank; Elmer Berghorn; Patrick J. Creaven
- Publisher
- Springer US
- Year
- 1995
- Tongue
- English
- Weight
- 529 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0167-6997
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## Background: Colorectal carcinoma is the third leading cause of cancer-related death. the primary treatment for patients with metastatic colorectal carcinoma is systemic chemotherapy with 5-fluorouracil (5-fu) and leucovorin (lv), a biomodulator of 5-fu that has been shown to enhance its activity
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