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Simultaneous Determination of Penicillin and Penicilloic Acid in Fermentation Samples by Colorimetric Method

✍ Scribed by Pan, S. C.

Book ID
125959165
Publisher
American Chemical Society
Year
1954
Tongue
English
Weight
901 KB
Volume
26
Category
Article
ISSN
0003-2700

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πŸ“œ SIMILAR VOLUMES

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I I ] Penicillin and the corresponding penicilloic acid are extracted by chloroform from an acidified sample of urine which has been partly saturated by ammonium sulfate. A portion of the extract is dried and redissolved in a small volume of acetone. A measured aliquot is chromatographed on a silica

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A method based o n paper chromatography and biological assay has been developed for the determination of p-hydroxyphenoxy methyl penicillin in phenoxy methyl penicillin (penicillin V) fermentation samples. The penicillin broth is extracted into methyl isobutyl ketone. The extract is chromatographed