A gas chromatographic/mass spectrometric assay for the anti-anaphylactic agent Ketotifen is described. The method is based on negative ion chemical ionization, utilizing the electrophoric nature of the underivatized drug. A simple procedure for deuteration of the intact target molecule is presented,
Simultaneous determination of metoproloi and deuterium-labelled metoprolol in human plasma by gas chromatography—negative-ion mass spectrometry
✍ Scribed by D. Gaudry; D. Wantiez; J. Richard; J.P. Metayer
- Book ID
- 108449881
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 355 KB
- Volume
- 339
- Category
- Article
- ISSN
- 0378-4347
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