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Determination of mannose and fructose in human plasma using deuterium labelling and gas chromatography/mass spectrometry

✍ Scribed by E. Pitkänen; T. Kanninen

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
566 KB
Volume
23
Category
Article
ISSN
1076-5174

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A gas chromatographic/mass spectrometric assay for the anti-anaphylactic agent Ketotifen is described. The method is based on negative ion chemical ionization, utilizing the electrophoric nature of the underivatized drug. A simple procedure for deuteration of the intact target molecule is presented,