Liquid chromatography with amperometric detection was employed for the determination of the dihydroxycatecholamine metabolites, 3,4-dihydroxyphenylethylene glycol (DOPEG) and 3,4\_dihydroxyphenylacetic acid (DOPAC) in plasma. The compounds were isolated from plasma by adsorption onto alumina, the el
Simultaneous assay of 3,4-dihydroxyphenylethylene glycol and norepinephrine in human plasma by high-performance liquid chromatography with electrochemical detection
โ Scribed by L.G. Howes; S. Miller; J.L. Reid
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 210 KB
- Volume
- 338
- Category
- Article
- ISSN
- 0378-4347
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๐ SIMILAR VOLUMES
We herein report the simultaneous determination of the levels of noradrenaline (NA), and 3-methoxy-4-hydroxyphenylglycol (MHPG), a major metabolite of NA. The sample was subjected to a Sep Pak C18 cartridge prior to the NA and MHPG assay by high-performance liquid chromatography with an electrochemi
A new method utilizing high-performance liquid chromatography with electrochemical detection for the determination of unconjugated 3-methoxy-4-hydroxyphenylglycol, a major metabolite of norepinephrine, in human plasma is described. A novel internal standard, 3-ethoxy-4-hydroxyphenylglycol, was used