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Simple total synthesis of prostaglandins from 4-cumyloxy-2-cyclopentenone

✍ Scribed by Stork, Gilbert; Isobe, Minoru


Book ID
111693797
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
224 KB
Volume
97
Category
Article
ISSN
0002-7863

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ChemInform Abstract: Enantioconvergent S
✍ T. SUGAHARA; K. OGASAWARA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 2 views

Enantioconvergent Synthesis of (+)-Estrone from Racemic 4-tert-Butoxy-2-cyclopentenone. -Starting from racemic cyclopentenone (I) (+)-estrone (XIII) is prepared in an enantioconvergent manner. Key steps are the lipase-mediated kinetic resolution of the alcohol (IV) and the Diels-Alder -retro-Diels-