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Cyclopentanones—XVI : Prostaglandin synthesis involving catalytic hydrogenation of 2,3-dialkyl-4-hydroxy-2-cyclopentenones

✍ Scribed by P. De Clercq; R. Coen; E. Van Hoof; M. Vandewalle


Book ID
103396864
Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
636 KB
Volume
32
Category
Article
ISSN
0040-4020

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Cyclopentanones. XII. An Alternative Syn
✍ R. Coen; P. De Clercq; D. van Haver; M. Vandewalle 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 165 KB

## Abstract A novel approach to Corey's aldehyde is described. A suitable substituted all cis 2, 3‐dialkyl‐l, 4‐cyclopentanediol system is obtained by catalytic reduction of 2, 3‐dialkyl‐4‐hydroxy‐2‐cyclopentenones. Epimerisation to the prostaglandin configuration occurs spontaneously when later on