ChemInform Abstract: Enantioconvergent S
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T. SUGAHARA; K. OGASAWARA
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Article
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2010
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John Wiley and Sons
β 35 KB
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Enantioconvergent Synthesis of (+)-Estrone from Racemic 4-tert-Butoxy-2-cyclopentenone. -Starting from racemic cyclopentenone (I) (+)-estrone (XIII) is prepared in an enantioconvergent manner. Key steps are the lipase-mediated kinetic resolution of the alcohol (IV) and the Diels-Alder -retro-Diels-