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Simple and efficient preparation of dihydropyrans and spiroketals using the intramolecular silyl modified Sakurai (ISMS) reaction

✍ Scribed by István E Markó; Daniel J. Bayston; Abdelaziz Mekhalfia; Harry Adams


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
239 KB
Volume
102
Category
Article
ISSN
0037-9646

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📜 SIMILAR VOLUMES


The intramolecular silyl modified sakura
✍ Abdelaziz Mekhalfia; István E Markó; Harry Adams 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 248 KB

By employing the intramolecular version of the SMS reaction, oxocenes, including spiroethers and spiroketals, can be prepared in a highly convergent, one-step operation. In the preceding communicationl, we have described our initial findings on a novel and powerful methodology -The Silyl Modified S

Regiocontrol in the intramolecular silyl
✍ István E. Markó; Abdelaziz Mekhalfia 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 248 KB

The ISMS reaction, which initially afforded a mixture of regioisomeric olefins, can now be controlled to produce only the exocyclic alkene. The ISMS methodology was used in a highly efficient synthesis of a Dacus oleae pheromone 8.