Silica supported perchloric acid: A mild and highly efficient heterogeneous catalyst for the synthesis of poly-substituted quinolines via Friedländer hetero-annulation
✍ Scribed by M. Narasimhulu; T. Srikanth Reddy; K. Chinni Mahesh; P. Prabhakar; Ch. Bhujanga Rao; Y. Venkateswarlu
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 160 KB
- Volume
- 266
- Category
- Article
- ISSN
- 1381-1169
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📜 SIMILAR VOLUMES
Poly-substituted quinolines were synthesized in the presence of a catalytic amount of dodecylphosphonic acid (DPA) in aqueous media and solvent-free conditions. The reactions proceed very well under relatively mild conditions, and DPA can be recycled.
## Abstract A rapid and an efficient method for the preparation of a variety of substituted quinolines has been developed through the reactions of __o__‐aminoarylketones with carbonyl compounds containing a reactive α‐methylene moiety in the presence of molten [Et~3~NH][HSO~4~] under solvent‐free c