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Friedländer synthesis of poly-substituted quinolines in the presence of triethylammonium hydrogen sulfate [Et3NH][HSO4] as a highly efficient, and cost effective acidic ionic liquid catalyst

✍ Scribed by Esmat Tavakolinejad Kermani; Hojatollah Khabazzadeh; Tayebeh Jazinizadeh

Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 105 KB
Volume: 48
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.683

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✦ Synopsis

Abstract

A rapid and an efficient method for the preparation of a variety of substituted quinolines has been developed through the reactions of o‐aminoarylketones with carbonyl compounds containing a reactive α‐methylene moiety in the presence of molten [Et~3~NH][HSO~4~] under solvent‐free conditions in high yields. J. Heterocyclic Chem., (2011).

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