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Friedländer synthesis of poly-substituted quinolines in the presence of dodecylphosphonic acid (DPA) as a highly efficient, recyclable and novel catalyst in aqueous media and solvent-free conditions

✍ Scribed by S. Ghassamipour; A.R. Sardarian

Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 235 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.09.097

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✦ Synopsis

Poly-substituted quinolines were synthesized in the presence of a catalytic amount of dodecylphosphonic acid (DPA) in aqueous media and solvent-free conditions. The reactions proceed very well under relatively mild conditions, and DPA can be recycled.

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