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o-Benzenedisulfonimide as a reusable Brønsted acid catalyst for an efficient and facile synthesis of quinolines via Friedländer annulation

✍ Scribed by Margherita Barbero; Stefano Bazzi; Silvano Cadamuro; Stefano Dughera


Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
211 KB
Volume
51
Category
Article
ISSN
0040-4039

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o-Benzenedisulfonimide as a reusable aci
✍ Margherita Barbero; Stefano Bazzi; Silvano Cadamuro; Stefano Dughera 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 309 KB

The synthesis of tetrahydroisoquinolines and tetrahydro-b-carbolines, using the Pictet-Spengler reaction, was carried out in the presence of a catalytic amount of o-benzenedisulfonimide, which worked as a Brønsted acid organocatalyst. The reaction conditions were mild and green and good target produ