Signalling by cGMP-dependent protein kin
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Arie B. Vaandrager; Hugo R. Jonge
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Article
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1996
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Springer
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English
⚖ 865 KB
The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent