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Regulation of innate immunity by cGMP and cGMP-dependent protein kinases

✍ Scribed by S. Davies; L. Aitchison; J. Dow


Book ID
113520401
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
69 KB
Volume
150
Category
Article
ISSN
1095-6433

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Signalling by cGMP-dependent protein kin
✍ Arie B. Vaandrager; Hugo R. Jonge πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 865 KB

The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent