Signalling by cGMP-dependent protein kin
โ
Arie B. Vaandrager; Hugo R. Jonge
๐
Article
๐
1996
๐
Springer
๐
English
โ 865 KB
The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent