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Genetic dissection of signaling via cGMP-dependent protein kinases

✍ Scribed by Robert Feil; Pascal Weinmeister; Robert Lukowski; Silke Weber; Sabine Brummer; Susanne Feil; Franz Hofmann


Publisher
BioMed Central
Year
2005
Tongue
English
Weight
187 KB
Volume
5
Category
Article
ISSN
1471-2210

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Signalling by cGMP-dependent protein kin
✍ Arie B. Vaandrager; Hugo R. Jonge πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 865 KB

The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent