Shift of private and not of cross-reactive anti-DNA idiotypes in systemic lupus erythematosus
โ Scribed by Ronsuke Suenaga; Nabih I. Abdou
- Book ID
- 118375384
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 860 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1090-2341
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๐ SIMILAR VOLUMES
Two common cross-reacting anti-DNA antibody idiotypes designated 1616 and 32/15, previously identified in the serum of patients who have systemic lupus erythematosus, were found in 24% and 7%, respectively, of 147 first-degree relatives. These findings imply that high-frequency germ-line genes exist
McLean ## Cross-reactivity of IgG anti-DNA-secreting B cells in patients with systemic lupus erythematosus This study is the first to analyze the cross-reactivity of in vivo activated B cells from patients with systemic lupus erythematosus. A chamber ELIspot assay was used to determine whether ly