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Cross-reactive idiotypes in anti-DNA antibodies of systemic lupus erythematosus patients

โœ Scribed by G.D. Harkiss; F. Hendrie; G. Nuki

Book ID
118374695
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
653 KB
Volume
39
Category
Article
ISSN
1090-2341

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Detection of cross-reactive anti-DNA ant
Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives
โœ Dr. D. A. Isenberg; Y. Shoenfeld; M. Walport; C. Mackworth-Young; C. Dudeney; A. ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 757 KB

Two common cross-reacting anti-DNA antibody idiotypes designated 1616 and 32/15, previously identified in the serum of patients who have systemic lupus erythematosus, were found in 24% and 7%, respectively, of 147 first-degree relatives. These findings imply that high-frequency germ-line genes exist