A method for determining the sex of human skeletons was developed using molecular genetic techniques. The amelogenin gene, found on the X and Y chromosomes, was examined using the polymerase chain reaction (PCR) and a nonradioactive dot blot procedure. DNA was analyzed from 20 modern individuals of
Sex determination using PCR
โ Scribed by Peter E. Kima; Madeline E. Rasche
- Publisher
- The American Society for Biochemistry and Molecular Biology
- Year
- 2004
- Tongue
- English
- Weight
- 89 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1470-8175
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Human sex determination is a fascinating topic, particularly at the level of molecular genetics, as it represents an excellent paradigm for mammalian organ development. Recent progress has seen the addition of several new pieces to this developmental jigsaw puzzle. In mammals, the Y chromosome is ma
## Abstract How is the embryonic bipotential gonad regulated to produce either an ovary or a testis? In males, transient early activation of the Y chromosome __Sry__ gene makes both germ cells and soma male. However, in females, available evidence suggests that the process of ovary sex determinatio
Although SRY was first identified 10 years ago, we still know remarkably little about its mode of action or downstream target genes. Recently, potential protein partners have been identified and there has been considerable activity to understand the roles of WT1, SF-1, DAX-1 and SOX9 in gonadogenesi