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Serotonin transporter gene (5-HTT) polymorphisms and compulsive buying

✍ Scribed by Devor, Eric J.; Magee, Harry J.; Dill-Devor, Rebecca M.; Gabel, Janelle; Black, Donald W.

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
9 KB
Volume
88
Category
Article
ISSN
0148-7299
DOI
10.1002/(sici)1096-8628(19990416)88:2<123::aid-ajmg5>3.0.co;2-s

No coin nor oath required. For personal study only.

✦ Synopsis

We examined a panel of 21 patients diagnosed with compulsive buying for two DNA sequence polymorphisms found in the gene that encodes the serotonin transport (5-HTT). One polymorphism, found in the promoter region of the 5-HTT gene, involves a 44-base pair (bp) deletion, and the other, found in the second intron, is due to variable numbers of a repeat sequence. We also typed a panel of 38 psychiatrically normal controls for both 5-HH markers. When compared to this control panel, no significant differences were seen for either 5-HTT marker among the compulsive buyers. Am.

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