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Separation of the enantiomers of coumarinic anticoagulant drugs by capillary electrophoresis using maltodextrins as chiral modifiers

✍ Scribed by Annick D'Hulst; Norbert Verbeke


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
480 KB
Volume
6
Category
Article
ISSN
0899-0042

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Following an extended chiral drug screening program by capillary zone electrophoresis (CZE), the enantioseparation of 86 racemic drugs was tested with β₯cyclodextrin as a chiral solvating agent. Unified conditions were applied to all experiments. In total, 18 drug racemates were separated, 13 entries