ChemInform Abstract: Chiral Separation of Drug Enantiomers by Capillary Electrophoresis Using Succinyl-β-cyclodextrin.
✍ Scribed by M. G. SCHMID; K. WIRNSBERGER; G. GUEBITZ
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The chiral separation of (±)‐catechin was investigated by capillary electrophoresis using characterized succinyl‐β‐cyclodextrins (Suc‐β‐CDs) with one to three degree of substitution values. The effects of nature and concentration of Suc‐β‐CDs and running buffer pH on the migration time
A negatively charged cyclodextrin, sulfated -cyclodextrin -CD-Ž y . x SO , was used as a chiral selector for capillary electrophoresis separations of 4 4 basic pharmaceutical enantiomers. The charges of the basic enantiomers were controlled by adjusting the buffer pH. At pH 2.5, basic compounds a