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Separation of tetracycline related substance by high-performance liquid chromatography on poly(styrene—divinylbenzene)

✍ Scribed by K. Wolfs; E. Roets; J. Hoogmartens; H. Vanderhaeghe

Book ID
108337250
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
252 KB
Volume
358
Category
Article
ISSN
1873-3778

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Separation of keto—enol tautomers of chl
Separation of keto—enol tautomers of chlortetracycline and 4-epichlortetracycline by liquid chromatography on poly(styrene—divinylbenzene)copolymer
✍ Weng Naidong; E. Roets; R. Busson; J. Hoogmartens 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 456 KB

Keto and enol tautomers of chlortetracycline and 4-epichlortetracycline were successfully separated by low temperature high-performance liquid chromatography on poly(styrene-divinylbenzene)copolymer. The keto-enol tautomerism occurs between C-11a and C-12. The elucidation of the chemical structure o