✦ LIBER ✦

Self-determinants in autoimmune demyelinating disease: changes in T- cell response specificity

✍ Scribed by Vincent K. Tuohy; Robert B. Fritz; Avraham Ben-Nun

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 722 KB
Volume: 6
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(94)90009-4

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✦ Synopsis

Recent research developments support the following views regarding antigen recognition in autoimmune demyelinating disease: there may be no single autoimmune target protein; diverse peptide self-determinants from multiple myelin proteins can be recognized; target determinant epitopes may differ among individuals; and target epitope recognition can change with time during the course of disease.

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