𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New complexities in helper T cell fate determination and the implications for autoimmune diseases

✍ Scribed by Hiroaki Takatori; Yuka Kanno; Zhi Chen; John J. O’Shea


Publisher
Springer
Year
2008
Tongue
English
Weight
288 KB
Volume
18
Category
Article
ISSN
1439-7595

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Degenerate TCR recognition and dual DR2
✍ Xin Zhang; Yunan Tang; Danuta Sujkowska; Jinzhao Wang; Vinod Ramgolam; Mireia So 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB 👁 1 views

## Abstract TCR degeneracy may facilitate self‐reactive T cell activation and the initiation of an autoimmune response in multiple sclerosis (MS). MHC class II alleles of the DR2 haplotype DR2a (DRB5\*0101) and DR2b (DRB1\*1501) are associated with an increased risk for MS in Caucasian populations.

Analysis of the T cell repertoire for my
✍ Yoh Matsumoto; Kazuhiro Kawai; Michio Fujiwara 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 860 KB

Analysis of the T cell repertoire for myelin basic protein in thymus-grafted and other types of chimera: evidence that major histocompatibility complex molecules on accessory cells rather than T cell specificity mainly regulate susceptibility to autoimmune encephalomyelitis\* Experimental autoimmune